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In histology, adipose tissue or body fat or just fat is loose connective tissue composed of adipocytes. It is technically composed of roughly only 80% fat; fat in its solitary state exists in the liver and muscles. Adipose tissue is derived from lipoblasts. Its main role is to store energy in the form of fat, although it also cushions and insulates the body. Obesity or being overweight in humans and most animals does not depend on body weight but on the amount of body fat—to be specific, adipose tissue. Two types of adipose tissue exist: white adipose tissue and brown adipose tissue. Adipose tissue also serves as an important endocrine organ by producing hormones such as leptin, resistin, and the cytokine TNFα. The formation of adipose tissue appears to be controlled by the adipose gene. Adipose tissue was first identified by the Swiss naturalist Conrad Gessner in 1551.
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