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via Wikipedia
A
serotonin–norepinephrine–dopamine reuptake inhibitor, or
triple reuptake inhibitor, is a
drug/
ligand that simultaneously acts as a
reuptake inhibitor for the
monoamine neurotransmitters,
serotonin,
norepinephrine and
dopamine, by blocking the
action of the
serotonin transporter,
norepinephrine transporter, and
dopamine transporter, respectively. This, in turn, leads to increased
extracellular concentrations of these
neurotransmitters and, therefore, an increase in
serotonergic,
noradrenergic or
adrenergic, and
dopaminergic neurotransmission. In this sense, to a degree, there is
omnipresence in what these compounds do. This group of
drugs/
ligands are believed to work in much the same way as the
nonselective monoamine releasers,
albeit through a differing mechanism of activity.
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